Primary Analysis Using F-S Method1

Study Endpoints   >   Primary   >   Primary Analysis

Primary analysis determined by the Finkelstein-Schoenfeld method, a hierarchical combination of both endpoints, prioritizing all-cause mortality.

Patients Alive at
Month 30*

% of Patients Alive
100
50
0
71%
n=186
57%
n=101
Pooled Tafamidis
n=264
Placebo
n=177

OF THE 287
SURVIVING
PATIENTS AT
MONTH 30

Average CV-related
Hospitalizations Per Patient Per
Year During 30 Months

Average Per Patient Per Year
1
0.5
0
0.30
0.46
Pooled Tafamidis
(n=186)
Placebo
(n=101)

p=0.0006; Win-Ratio1 (95% CI) = 1.70 (1.26-2.29)

*Heart transplantation, combined heart and liver transplantation, and cardiac mechanical assist device implantation are treated as equivalent to death in this analysis.

CI: confidence interval; CV: cardiovascular.