Background on Transthyretin1

Transthyretin Amyloid Cardiomyopathy   >   ATTR-CM   >   Pathogenesis, Subtypes and Diagnosis

TRANSTHYRETIN
Transporter of thyroxine
and retinol

  • Transthyretin is a protein produced by the TTR gene
  • Transthyretin transports thyroxine and retinol (vitamin A) in blood
  • Normally, transthyretin protein exists in the serum as a soluble tetramer
  • Transthyretin is produced principally in the liver, although also in the retina and the choroid plexus in the brain